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Paper Highlights

Research Article   February 3, 2020
Genet. Mol. Res.: 19(1): 1-10.

Uncoupling Proteins and Cardiac Apoptosis in High Fat Diet-Fed Male Rats

This study aimed to assess impact of high fat diet (HFD) on cardiac apoptosis, and cardiac uncoupling proteins (UCPs) 2&3 expression. Twenty rats were fed either (45%) or (10%) fat diet for 6 months, then cardiac tissue expression of BAX, Bcl2, Fas, Fas-L (markers for apoptotic pathways) and UCP 2&3 were assessed. Results revealed enhancement of intrinsic and extrinsic cardiomyocyte apo.. Read More»

Research Article   September 5, 2019
Genet. Mol. Res.: 18(3): 1-14.

Electroporation induced membrane permeability changes at the ionic level

Background/Aim: Electrochemotherapy is an innovative method for the localized treatment of cutaneous and subcutaneous metastatic cancers. The aim of the study is to assess the changes at the plasma membrane and its recovery time by monitoring the regulated passage of ions through specific ion channels as measured by electrophysiology. Materials and Methods: Electroporation and patch cla.. Read More»

Research Article   July 5, 2019
Genet. Mol. Res.: 18(3): 1-11.

Novel polymorphisms in the PLIN2 gene of Nellore cattle

Genetic variations in genes involved in lipid storage, which also may interfere with important phenotypic traits such as intramuscular fat deposition in cattle, can represent useful markers in marker assisted selection programs. An important candidate gene is perilipin 2 (PLIN2) that plays a role in the capture of long chain fatty acids and in the formation and stabilization of lipid d.. Read More»

Research Article   July 5, 2019
Genet. Mol. Res.: 18(3): 1-13.

Exome Sequencing Studies for Kids with Non-Familial Food Allergy

Introduction: Food allergies (FA) have been increasing dramatically over the past 25 years and the peanut allergy has been noticed more likely for a half-decade as well. The prevalence of FA in children was found to be 10%, which is high compared with adults. Limited periodic reports are available of numerous food allergic reactions in children. Complete exome sequencing in thi.. Read More»

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